The Premier League enters Game Week 22 – which means we are well over the halfway stage of this season.

And it all kicks off at Old Trafford, where Manchester United welcome Manchester City on Saturday lunchtime.

Although the Manchester Derby is the most anticipated clash of this weekend, there will be other key games later in the day.

So, what matches can we expect upsets?

1. Chelsea vs Brentford: This will be Liam Rosenior’s third game in charge of Chelsea, since he replaced Enzo Maresca. The only match he has won is the 4-1 drubbing of Charlton in the FA Cup. Brentford are the visitors this Sunday and they arrive sitting in fifth place – above the Blues. With Igor Thiago in brilliant form, the Bees could sting at Stamford Bridge.

2. Liverpool vs Burnley: This season especially, Anfield has not been the intimidating stadium it is renowned for, with a few unfancied teams picking up good results there. Burnley are the visitors this weekend and what many people don’t give Clarets credit for is they can be a good side. Manchester United found out last weekend.

3. Nottingham Forest vs Arsenal: Mikel Arteta’s men have not been so convincing even in the matches they picked up three points. Against Liverpool last weekend, they failed to find the back of the net at home. At Forest this Saturday, Arsenal could come up against Sean Dyche’s well-drilled defence and if they are not on top of their game, they might drop points.