A MOTHER has opened up on the savage side effects she has experienced in just four weeks on Mounjaro.
Megan Tilbury, a from East Sussex, was previously on the but had to take a break to have a .




Now, after giving birth to her second child, the is back using , which have been hailed the ‘King Kong of fat jabs.’
The topped the scales at 17 stone 13 lbs when she went back on for the second time and in just four weeks, has lost 1 stone 6 lbs.
But despite weighing in at 16 stone 7 lbs, Megan has experienced some .
When she first used the jabs, she didn’t deal with any side effects, so it’s no surprise that this has really “hit her by surprise.”
Posting on , the mother opened up about her Mounjaro experience, as she admitted: “, Peppermint tea, and Dioralyte have been my best friends for the past four days.”
Getting candid on her side effects, Megan said: “Here’s a Mounjaro update that no one asked for but everyone needs.
“I’ve lost 7 lb in the last [three days] because I went up to 5mg.
“I can’t keep anything in me, all I’m doing is having .
“And then I just ate some mouldy bread by accident and now I feel sick.”
As well as having to , the young woman has also been experiencing , which have been described as ‘eggy burps.’
She continued: “I’ve also got sulphur burps.
“All of this completely hit me by surprise. When I took last time, I went up to 7.5mg before getting pregnant and I did not have one side effect.
Even had me cleaning at 3am yesterday because the pain from laying down was too much
Megan Tilbury
“This is really hitting me by surprise, I didn’t expect this to happen.
“I guess it just goes to show, when you take a break from medication and start it again, it doesn’t mean you’re gonna have the same symptoms as before.”
Everything you need to know about fat jabs
Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases.
Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK.
Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market.
Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year.
How do they work?
The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight.
They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists.
They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients’ sugar levels are too high.
Can I get them?
NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics.
Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure.
GPs generally do not prescribe the drugs for weight loss.
Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk.
Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health.
Are there any risks?
Yes – side effects are common but most are relatively mild.
Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea.
Dr Sarah Jarvis, GP and clinical consultant at patient.info, said: “One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.”
Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia.
Evidence has so far been inconclusive about whether the injections are damaging to patients’ mental health.
Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines.
Not only this, but Megan then confirmed that the side effects are “always worse at night.”
So much so, she shared: “Even had me cleaning at 3am yesterday because the pain from laying down was too much.”
Mounjaro users react
Megan’s clip, which she shared on her account under the username @ megantilbury , has clearly left many open-mouthed, as it has quickly racked up 1,427 likes and 177 comments.
But it appears it’s not just Megan experiencing such side effects, as numerous other fat jab users eagerly raced to the comments to share their own experiences.
I gave up after nine weeks because the side effects were just non-stop
TikTok user
One person said: “In the same boat oh my god. I ended up in A&E yesterday…. I also lost 9kg so far and started about 5 weeks ago.”
Another added: “I had to come off Mounjaro. I was absolutely ill with nausea and sickness. I’m now on .”
A third commented: “Sulphur burps are the absolute worst thing, can’t convince me any different. I’m so sorry.”
Meanwhile, someone else chimed in and explained: “I gave up after nine weeks because the side effects were just non-stop. They weren’t always bad but it was exhausting having a funny tummy all the time.”