FAT jabs have taken over the nation, with 2.5million Brits estimated to be using them and dozens of celebrities showcasing shrinking waistlines on red carpets.
While some stars have declined to comment on their weight loss, other famous faces have admitted to using injections such as and
Singing sensation Lizzo has recently undergone a significant body transformationCredit: Getty – Contributor
Lizzo showed off her recent weight loss as she stripped to a shimmering one-pieceCredit: Instagram
The effects have often been dramatic, with some hailing the jabs as “life-changing” and “effortless”.
However, others have been open about some like nausea and gallbladder issues.
For some, losing a few pounds has been a huge confidence boost, with many sharing bikini-clad snaps with their millions of followers.
Here we look at who is stripping off for following their head-turning transformations….
Lizzo: ‘Ozempic works because you eat less food. ‘
For years, singer garnered a fierce fan base thanks to her body-confident mantra and head-turning curves.
Recently, the Michigan-born songstress, 37, admitted that she has used Ozempic to help achieve a 60lb weight loss.
In a chat on Trisha Paytas’ Just Trish podcast , she said she had “tried everything” in her slimming mission, including using the weight loss drug in 2023.
Lizzo, whose real name is Mellissa Viviane Jefferson, appears to be proud of her weight loss journey, which has seen her lower her BMI by 10.5 points.
Despite fans ”, last Lizzo flashed her slimmed-down figure in a
Lizzo has insisted that she has since decided against continuing Ozempic, arguing that counting calories has proved to be the best approach for her.
She told the podcast: “It’s just the for me, calories in versus calories out.
“Ozempic works because you eat less food. .
“It makes you feel full, so if you can just do that on your own and get mind over matter, it’s the same s**t.”
Gemma Collins: ‘It’s been effortless’
Gemma Collins has been reality TV’s poster girl for curvy womenCredit: Not known clear with Picture Desk
Gemma recently displayed a noticeably slimmer frame, as shown with this cut out swimsuitCredit: Instagram
Reality powerhouse , who has embraced her curvy figure for more than a decade, exclusively told The Sun last year that .
The legend, 45, revealed that at her heaviest – 23 stone and a dress size 26 – she was left unable to roll over in bed or wear sexy lingerie.
After years of yo-yo diets, in 2025, Gemma shared how she used NHS-approved injections and dropped a total of three-and-a-half stone and slimmed to a size 22.
Gemma found the results life-changing, and told The Sun: “I can’t believe I’ve finally found something that works.
“It’s been completely effortless – I don’t even want to eat anymore!
“I got on the scales and lost something like six kilograms in my first week…It’s been effortless.”
Gemma dropped three-and-a-half stone with MounjaroCredit: Instagram
Proud of her weight loss, Gemma has shown off her stunning figure in several recent holiday snaps.
Despite her success, Gemma admitted she was forced to stop the jabs temporarily after she was left in “excruciating” pain back in August.
She told the Mirror : “I had to stop the jabs for a bit because I had a gallbladder attack in August, but they’ve assured me that it’s not actually linked to Mounjaro.”
Gemma claims she “fell to the floor” while celebrating fiancé Rami Hawash’s birthday at a track.
According to the Oxford Online Pharmacy, gallbladder issues are one of the rare side effects of Mounjaro, which can occur in fewer than one in 100 people.
The star hasn’t been put off the jabs for good, though, and said: “I’ve given it a rest and I’ve really been managing what I’ve been eating.”
Serena Williams: ‘I’m perfectly me’
Serena Williams did a deep dive into Mounjaro before starting the jabCredit: Splash
The tennis legend has been retired from the sport for nearly four years now but has noticeably slimmed down and toned upCredit: Instagram
icon has experienced with the aid of weight-loss jabs.
, the mum-of-two, 44, wrote on this month: “I am not perfect….but I’m perfectly me.
“Take out time today to celebrate being perfectly you!”
The seven-time champion shared how she had tried to lose weight naturally after the birth of her two daughters, but had sought medical help.
Although she was initially hesitant, she has revealed she has been helped by a weight loss drug called Zepbound, similar to medications like Ozempic that have become increasingly popular.
Serena has had a 31lb weight loss after using ZepboundCredit: Refer to Caption
Serena – whose husband has invested in a weight loss firm – insists she still works out, uses cryotherapy, and eats healthy to get the figure she wants.
Serena told People Magazine at the time: “I did a lot of research on it.
“I was like, ‘Is this a shortcut? What are the benefits? What are not the benefits?’
“I really wanted to dive into it before I just did it.”
Serena previously opened up to Porter about struggling with her body shape as a world-class athlete.
Everything you need to know about fat jabs
Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases.
Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK.
Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market.
Mounjaro accounts for most private prescriptions for weight loss.
How do they work?
The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight.
They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists.
They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients’ sugar levels are too high.
Can I get them?
NHS prescriptions of Wegovy is controlled through specialist weight loss clinics, while Mounjaro is available from GPs but only for the highest risk patients.
For Wegovy, a patient will typically have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure. They will be expected to have tried diet and exercise already.
Mounjaro is available from NHS GPs for weight loss but only to a tiny group of patients, with the rollout starting with those with a BMI higher than 40 and with four weight-related health conditions.
Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk.
Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health.
Are there any risks?
Yes – side effects are common but most are relatively mild.
Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea.
Dr Sarah Jarvis, GP and clinical consultant at patient.info, said: “One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.”
Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia.
Evidence has so far been inconclusive about whether the injections are damaging to patients’ mental health.
She shared: “It was hard because when I was playing in the beginning – the first 15 years – my body was different. I had big boobs, I had a big butt.
“Every athlete was like super flat, super thin and beautiful, but in a different way. And I didn’t understand as an athlete how to deal with that.
“It does affect you mentally. Absolutely. You think you’re large for your whole life, and you look [back] and you’re like, I was fit.”
Speaking about her confidence now, she added: “I want to leave behind , doubt and second-guessing myself.
“I want to bring in more clarity, confidence that I made the right decisions and that you don’t always have to live only for your children. I’m discovering me again.”
Amy Tapper: ‘Trying to lose weight became my full-time job’
At her heaviest, Gogglebox’s Amy Tapper was a size 26Credit: Do The Unthinkable
Now Amy is a size 18 thanks to using ‘life-changing’ MounjaroCredit: Lorna Roach
Amy insisted she felt like there was ‘nothing else she could do’ apart from try the jabsCredit: Not known, clear with picture desk
She praised the injection for giving her ‘peace’ for once in her lifeCredit: Instagram
‘s is another reality star to transform their figure using Mounjaro, and has hailed its effect as being “life-changing”.
Last August, she confirmed that she had shed a whopping following the jabs.
Amy, 26, dropped from a size 26 to a size 18 in just 12 months, after previously admitting that trying to slim down had been a lifelong battle.
Showing off her new figure in an exclusive photoshoot with Fabulous, Amy revealed: “I have done every single diet under the sun.
“The same thing happens over and over again. I get three stone lighter and I don’t lose any more. Trying to lose weight became my full-time job.”
Speaking about turning to jabs for help, she revealed: “I felt there was nothing else I could do.
“I actually went to a doctor about surgery, because it got past the point of caring about how I look.”
After starting , Amy recognised: “I’m fitting into size 18 clothes for the first time since I was 15 or 16 – it’s hard for me to believe.
“It’s changed my life. I went to the the other night, and when I sat down, my thighs weren’t touching the person next to me, or the sides of the chairs. I had room.”
Amy, who also starred on matchmaking show in 2018, added that she finds it frustrating when ”, and said: “I don’t want people to think that I’ve sat around for the last 17 years of my life not trying to lose weight.
“I want people to know that this has been my only option to get this far.”
Meghan Trainor: ‘I feel great’
Meghan Trainor has admitted to using MounjaroCredit: Rex
The singer has lost over four stone and said she’s aiming to be the ‘healthiest version of herself’Credit: Getty
Fans of Grammy winner Meghan Trainor were left shocked at the star’s following the use of Mounjaro.
After much speculation, the singer, 32, revealed she was becoming the “healthiest version of herself” for her children, and didn’t gate-keep her jabs.
Mum-of-three Meghan, who is a coach on , shared: “I’ve worked with a dietician, made huge lifestyle changes, started exercising with a trainer, and yes, I used science and support (shoutout to Mounjaro!) to help me after my 2nd pregnancy.
“And I’m so glad I did because I feel great.”
Meghan, who has lost over four stone, revealed she had used the weight loss method alongside her husband, , and has been flaunting her new figure on social media.
Amy Schumer: ‘I wanted to keep it real with you’
Amy Schumer confirmed she had tried Ozempic but stopped shortly after due to the side effectsCredit: Getty
She shared a filter-free snap recently showing off her 3 stone 5 lbs weight lossCredit: Instagram
Actress has built up a loyal fanbase thanks to her honest confessions, and she hasn’t held back when talking about her use of weight loss injections, too.
Amy, 44, has revealed she has tried both Ozempic and Mounjaro, with varying results.
In 2023, she confessed she had first tried Ozempic “about a year ago”; however, the medication hadn’t agreed with her.
She said on with : “I was one of the people that felt sick, I couldn’t play with my son.”
“You’re like, ‘OK, this isn’t livable for me,’ but I immediately invested because I’m like, ‘Everyone and their mom is going to try it’.”
In 2025, Amy then revealed she had been back on the , and said: “Mounjaro’s been great… I’m having a really good experience with it, and I wanted to keep it real with you about that.”
Now she has lost a total of 3 stone 5 lbs, but said her pet peeve is when other celebrities lie about using the jabs.
She claimed: “Everybody (is) lying, everyone’s like, ‘Oh, smaller portions,’ like shut the f**k up, you’re on Ozempic or one of those things. Just be real with the people.”
Rebel Wilson: ‘My relationship with food is complicated’
Rebel Wilson, pictured here before her weight loss, used Ozempic to shed a whopping 5 stone 7 lbsCredit: Reuters
The Pitch Perfect actress originally decided to slim down following advice from her IVF doctor in 2019Credit: Not known, clear with picture desk
Many people speculated had used weight loss jabs after she lost back in 2021.
The Pitch Perfect icon, 46, previously claimed to have successfully reached her 11 stone 7 lbs goal weight through high-intensity interval workouts and long hikes, complemented by a high-protein, low-sugar diet.
However, she told The Sunday Times : “Someone like me could have a bottomless appetite for sweets, so I think those can be good.
“I feel strongly that young women shouldn’t try to obsess over looking like Victoria’s Secret – they should just look like themselves.
“I know that my relationship with food is complicated.”
Rebel felt her weight loss wasn’t welcomed by industry peersCredit: instagram.com/rebelwilson
The Australian actress, who suffers from , a condition which affects , originally decided to slim down following advice from her IVF doctor in 2019.
But due to her trope of playing “fat funny characters” in films, she felt her weight loss wasn’t welcomed by industry peers.
She said: “Basically, no one apart from my mum wanted me to lose weight.
“People thought I’d lose my pigeonhole in my career – playing the fat funny character – and they wanted me to continue in that.”
What are the side effects of weight loss jabs?
Like any medication, weight loss jabs can have side effects.
Common side effects of injections such as Ozempic include:
Nausea: This is the most commonly reported side effect, especially when first starting the medication. It often decreases over time as your body adjusts.
Vomiting: Can occur, often in conjunction with nausea.
Diarrhea: Some people experience gastrointestinal upset.
Constipation: Some individuals may also experience constipation.
Stomach pain or discomfort: Some people may experience abdominal pain or discomfort.
Reduced appetite: This is often a desired effect for people using Ozempic for weight loss.
Indigestion: Can cause a feeling of bloating or discomfort after eating.
Serious side effects can also include:
Pancreatitis: In rare cases, Ozempic may increase the risk of inflammation of the pancreas, known as pancreatitis, which can cause severe stomach pain, nausea, and vomiting.
Kidney problems: There have been reports of kidney issues, including kidney failure, though this is uncommon.
Thyroid tumors: There’s a potential increased risk of thyroid cancer, although this risk is based on animal studies. It is not confirmed in humans, but people with a history of thyroid cancer should avoid Ozempic.
Vision problems: Rapid changes in blood sugar levels may affect vision, and some people have reported blurry vision when taking Ozempic.
Hypoglycemia (low blood sugar): Especially if used with other medications like sulfonylureas or insulin.
Eze Chidiebere Paul
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